Analgesic An analgesic drug, also called simply an analgesic, pain reliever , or painkiller , is any member of the group of drugs used to achieve relief from pain (that is, analgesia or pain management). Analgesics are conceptually distinct from anesthetics, which temporarily reduce, and in some instances eliminate, sensation, although analgesia and anesthesia are neurophysiologically overlapping and thus various drugs have both analgesic and anesthetic effects. Example Paracetamol Aceclofenac Nimesulide Chlorzoxazone Diclofenac Tramadol